Doc. Pavel Štarha, Ph.D.

Contact:

Email: pavel.starha@upol.cz
Address: 17. listopadu 12, Olomouc
Phone: (+420) 58 563 4340 (or 4346)
Fax: (+420) 58 563 4357

Qualification

2006 Mgr., Teaching of Chemistry and Biology, Palacký University in Olomouc
2010 Ph.D., Inorganic Chemistry, Palacký University in Olomouc
2006 – 2010 Researcher, Dept. Inorganic Chemistry, Faculty of Science, Palacký University in Olomouc
from 2010 Lecturer, Dept. Inorganic Chemistry, Faculty of Science, Palacký University in Olomouc
from 2010 Junior Researcher, Regional Centre of Advanced Technologies and Materials in Olomouc

Research interests

  • Transition metal complexes (Pt, Au, Ir, Ru, Os, Rh, Pd, Cu atd.)
  • Targeted drug transport – iron oxide-based nanomaterials, liposomes
  • Biological (cytotoxic, antiradical, etc.) activity of transition metal complexes
  • Thermal analysis (TG, DTA, DSC), isothermal titration calorimetry (ITC), atomic absorption spectroscopy (AAS), scanning electron microscopy (SEM), energy-disperse spectroscopy (EDS)

Publication activity

  • Publications (WoS): 38
  • Citations (WoS): 213
  • H-index: 9
  • Patents: 1 European patent (EP2636410 B1), 4 national patents (CZ 305374 B6, CZ 303560 B6, CZ 303417 B6, CZ 302623 B6)

Foreign research stays

  • From March to May 2008 – Juniata College, Huntingdon, PA, USA (study of guanine-N-oxides and their transition metal, especially platinum(II), complexes)
  • August 2014-January 2015 – research stay in the prof. Sadler group (University of Warwick)

Further activities

  • Principal investigator of FRVŠ project (1822/2011/F6) „Teaching innovation and preparation of practical exercises of the subject Thermal analysis“
  • Principal investigator of FRUP 2014_2_095 project „Innovation of laboratory for teaching of chemistry practices

Selected publications

Z. Trávníček, P. Štarha, Z. Dvořák, Dichlorido complexes of platinum with 7-azaindole halogeno-derivatives for use in the treatment of tumour diseases, Univerzita Palackého v Olomouci, evropský patent EP2636410 B1 (04/2015).

Z. Trávníček, P. Štarha, Z. Dvořák, Dijodo-komplexy platiny a jejich použití pro přípravu léčiv k léčbě nádorových onemocnění, Univerzita Palackého v Olomouci, patentový spis CZ 305374 B6 (07/2015).

Z. Trávníček, P. Štarha, I. Popa, Dichlorido komplexy platiny s halogenderiváty 7-azaindolu, způsob jejich přípravy a použití těchto komplexů jako léčiv v protinádorové terapii, Univerzita Palackého v Olomouci, patentový spis CZ 303417 B6 (07/2012).

Z. Trávníček, P. Štarha, J. Vančo, T. Šilha, J. Hošek, P. Suchý Jr., G. Pražanová, Anti-inflammatory active gold(I) complexes involving 6 substituted-purine derivatives, J. Med. Chem. 55 (2012) 4568–4579.

J. Hošek, J. Vančo, P. Štarha, L. Paráková, Z. Trávníček, Effect of 2-Chloro-Substitution of Adenine Moiety in Mixed-Ligand Gold(I) Triphenylphosphine Complexes on Anti-Inflammatory Activity: The Discrepancy between the In Vivo and In Vitro Models, PLOS ONE, 8 (2013) e82441.