Mgr. Radka Křikavová, Ph.D.

Contact:

Email:radka.krikavova@upol.cz
Address: 17. listopadu 12, Olomouc
Phone: (+420) 54 563 4353, 4340
Fax: (+420) 54 563 4357

Qualification

2007 Mgr., Teaching of Chemistry and English Philology, Palacký University in Olomouc
2012 Ph.D., Inorganic Chemistry, Palacký University in Olomouc
2007 – 2008 Researcher, Dept. Inorganic Chemistry, Faculty of Science, Palacký University in Olomouc
from 2010 Junior Researcher, Regional Centre of Advanced Technologies and Materials in Olomouc

Research interest

  • Transition metal complexes (Zn, Cu, Pt, Pd, Au, etc.)
  • Biological (cytotoxic, antiradical, anti-inflammatory, etc.) activity of transition metal complexes
  • NMR spectroscopy

Publication activity

  • Number of publications: 15
  • Number of citations (Scopus): 64
  • H-index: 4
  • Patents: 1 national patent (CZ 305411 B6)

Foreign research stays:

  • April-July 2011 – Austria, group of prof. Wolfgang Linert, Institute of Applied Synthetic Chemistry, Vienna University of Technology

Further activities

Principal investigator of FRVŠ project (3051/2011/G6) „Innovation of the course Methods for characterization of inorganic compounds – Spectral methods“

Selected publications

Trávníček, Z.; Novotná, R.; Dvořák, Z., Dichlorido komplexy platiny obsahující deriváty kinetinu, způsob přípravy a jejich užití jak léčiv v protinádorové terapii, Univerzita Palackého v Olomouci, patentový spis CZ 305411 B6 (08/2015).

Křikavová, R., Hošek, J., Vančo, J., Hutyra, J., Dvořák, Z., Trávníček, Z., Gold(I)-triphenylphosphine complexes with hypoxanthine-derived ligands: In vitro evaluations of anticancer and anti-inflammatory activities, PLoS ONE 9 (2014) e107373.

Křikavová, R., Hošek, J., Suchý, P., Vančo, J., Trávníček, Z., Diverse in vitro and in vivo anti-inflammatory effects of trichlorido-gold(III) complexes with N6-benzyladenine derivatives, J. Inorg. Biochem. 134 (2014) 92–99.

Hošek, J., Novotná, R., Babula, P. Vančo, J., Trávníček, Z., Zn(II)-Chlorido Complexes of Phytohormone Kinetin and Its Derivatives Modulate Expression of Inflammatory Mediators in THP-1 Cells, PLoS ONE 8 (2013) e65214.

Trávníček Z., Matiková-Maľarová M., Novotná R., Vančo J., Štěpánková K., Suchý P., In vitro and in vivo biological activity screening of Ru(III) complexes involving 6-benzylaminopurine derivatives with higher pro-apoptotic activity than NAMI-A, J. Inorg. Biochem. 105 (2011) 937–948.

Trávníček Z., Novotná R., Marek J., Popa I., Šipl M., Transformations of the natural cytokinin N6-isopentenyladenine in aqueous acidic media: structural aspects, Org. Biomol. Chem. 9 (2011) 5703–5713.