Prof. RNDr. Zdeněk Trávníček, Ph.D.

Contact:

Email: zdenek.travnicek@upol.cz
Address: Regional Center of Advanced Technologies and Materials & Department of Inorganic Chemistry, Faculty of Science, Palacky University in Olomouc, 17. listopadu 12, 771 46 Olomouc, Czech Republic
Phone: (+420) 585 634 352
Fax: (+420) 585 634 954


Education and Career

1989 MSc degree (in Inorganic Chemistry)
1996 PhD. degree (in Inorganic Chemistry)
2004 Full Professor of Inorganic Chemistry
since 2006 Head of the Department of Inorganic Chemistry, Faculty of Science, Palacky University in Olomouc, Czech Republic
since 2010 Leader of Research Programme ” Biologically-active Complexes and Molecular Magnets” of the Regional Centre of Advanced Technologies and Materials

Research Activities

  • Preparation and characterization of a new type of selected transition metal biologically active complexes and study of molecular magnets and molecular switches based on paramagnetic transition metal complexes.
  • Synthesis of hybrid molecular-crystalline nanostructures with a functionalized nanocrystalline oxidic carrier and a bound coordination compound for the use in the area of magnetic applications and targeted drug transport.
  • In vitro and in vivo testing of a wide spectrum of biological activities.

Publication activities

Other

Grants:

GAČR (e.g. Functionalized iron oxide nanoparticle-based magnetic carriers with bound biologically active and/or magnetically appealing compounds, P207/11/0841, 2011–2014), FRVŠ and other MŠMT projects (e.g. Research Intention „Transition metal complexes and oxides usable in bio-applications and nanotechnologies“, MSM6198959218, 2005–2011, 136 mil. Kč), IGA-PřF UP.

Teaching:

Supervised more than 10 PhD and 20 diploma theses since 1996.

Society Membership:

  • Czech Chemical Society
  • Czech and Slovak Crystallographic Association
  • American Chemical Society

Selected Publications

J. Hošek, J. Vančo, P. Štarha, L. Paráková, Z. Trávníček, “Effect of 2-Chloro-Substitution of Adenine Moiety in Mixed-Ligand Gold(I) Triphenylphosphine Complexes on Anti-Inflammatory Activity: The Discrepancy between the In Vivo and In Vitro Models“, PLOS ONE, vol. 8, pp. e82441, 2013. IF2012 = 3.353.

R. Herchel, Z. Trávníček, “5-Aminotetrazole induces spin crossover in iron(iii) pentadentate Schiff base complexes: Experimental and theoretical investigations“, DALTON TRANSACTIONS, vol. 42, pp. 16279-16288, 2013. IF2012 = 3.806.

T. Šilha, I. Nemec, R. Herchel, Z. Trávníček, “Structural and magnetic characterizations of the first manganese(iii) Schiff base complexes involving hexathiocyanidoplatinate(iv) bridges“, CRYSTENGCOMM, vol. 15, pp. 5351-5358, 2013. IF2012 = 3.879.

J. Hošek, R. Novotná, P. Babula, J. Vančo and Z. Trávníček, “Zn(II)-Chlorido Complexes of Phytohormone Kinetin and Its Derivatives Modulate Expression of Inflammatory Mediators in THP-1 Cells“, PLOS ONE, vol. 8, pp. e65214, 2013. IF2012 = 3.353.

I. Nemec, M. Machata, R. Herchel, R. Boča and Z. Trávníček, “A new family of Fe2Ln complexes built from mononuclear anionic Schiff base subunits“, DALTON TRANSACTIONS, vol. 41, pp. 14603-14610, 2012. IF2012 = 3.806.

Z. Trávníček, P. Štarha, J. Vančo, T. Šilha, J. Hošek, P. Suchý Jr. and G. Pražanová, “Anti-inflammatory active gold(I) complexes involving 6‑substituted-purine derivatives“, JOURNAL OF MEDICINAL CHEMISTRY, vol. 55, iss. 10, pp. 4568-4579, 2012. IF2011 = 5.248.

I. Nemec, R. Herchel, I. Salitros, Z. Travnicek, J. Moncol, H. Fuess, M. Ruben and W. Linert, “Anion driven modulation of magnetic intermolecular interactions and spin crossover properties in an isomorphous series of mononuclear iron(III) complexes with a hexadentate Schiff base ligand“, CRYSTENGCOMM, vol. 14, pp. 7015–7024, 2012. IF2011 = 3.842.

B. Lišková, L. Zerzánková, O. Nováková, H. Kostrhunová, Z. Trávníček and V. Brabec, “Cellular Response to Antitumorcis-Dichlorido Platinum(II) Complexes of CDK Inhibitor Bohemine and Its Analogues“, CHEMICAL RESEARCH IN TOXICOLOGY, vol. 25, iss. 2, pp. 500–509, 2012. IF2011 = 3.779.

R. Herchel, Z. Trávníček, and R. Zbořil, “Tuning of the Critical Temperature in Iron(II) Spin-Crossover Materials Based on Bridging Polycyanidometallates: Pentacyanidonitrosylferrate(II) and Hexacyanidoplatinate(IV)”,INORGANIC CHEMISTRY, vol. 50, iss. 24, pp. 12390-12392, 2011. IF2010 = 4.325.

Z. Trávníček, R. Novotná, J. Marek, I. Popa, and M. Šipl, “Transformations of the natural cytokinin N6-isopentenyladenine in aqueous acidic media: structural aspects“, ORGANIC & BIOMOLECULAR CHEMISTRY, vol. 9, iss. 16, pp. 5703-5713, 2011. IF2010 = 3.451.

R. Herchel, J. Tuček, Z. Trávníček, D. Petridis, and R. Zbořil, “Crystal Water Molecules as Magnetic Tuners in Molecular Metamagnets Exhibiting Antiferro-Ferro-Paramagnetic Transitions,”INORGANIC CHEMISTRY, vol. 50, iss. 18, pp. 9153-9163, 2011. IF2010 = 4.325.

Z. Trávníček, M. Matiková-Malarová, R. Novotná, J. Vančo, K. Štepankova, and P. Suchý, “In vitro and in vivo biological activity screening of Ru(III) complexes involving 6-benzylaminopurine derivatives with higher pro-apoptotic activity than NAMI-A,”JOURNAL OF INORGANIC BIOCHEMISTRY, vol. 105, iss. 7, pp. 937-948, 2011.IF2010 = 3.317.

I. Nemec, R. Herchel, R. Boča, Z. Trávníček, I. Svoboda, H. Fuess and W. Linert, “Tuning of spin crossover behaviour in iron(iii) complexes involving pentadentate Schiff bases and pseudohalides,“ DALTON TRANSACTIONS, vol. 40, iss. 39, pp. 10090-10099, 2011. IF2010 = 3.647.

R. Buchtík, Z. Trávníček, J. Vančo, R. Herchel, and Z. Dvořák, “Synthesis, characterization, DNA interaction and cleavage, and in vitro cytotoxicity of copper(II) mixed-ligand complexes with 2-phenyl-3-hydroxy-4(1H)-quinolinone,”DALTON TRANSACTIONS, vol. 40, iss. 37, pp. 9404-9412, 2011. IF2010 = 3.647.

R. Herchel, L. Pavelek, and Z. Trávníček, “Dinuclear and 1D iron(III) Schiff base complexes bridged by 4-salicylideneamino-1,2,4-triazolate: X-ray structures and magnetic properties“, DALTON TRANSACTIONS, vol. 40, iss. 44, 11896-11903, 2011.