Degrees and Professional Qualifications:
- since 2013 – deputy head of R-lab, RCPTM
- since 2012 – Junior Researcher, Regional Centre of Advanced Technologies and Materials (RCPTM)
- since 2007- Postdoc position, Department of Analytical Chemistry, UPOL
- 2009 – Ph.D. in analytical chemistry, Palacký University Olomouc
- 2008 – RNDr. in analytical chemistry, Palacký University Olomouc
- 2005 – Mgr. in analytical chemistry, Palacký University Olomouc
International Experience:
- 2013, 2012, 2011 – Department of Chemistry and Biochemistry, University of Texas, Arlington, USA; Assoc. Prof. Kevin A. Schug (5 months in total)
- 2007 – Department of Analytical Chemistry and Food Chemistry, University of Vienna, Rakousko; Prof. Wolfgang Lindner (3 months)
Research activities:
- Hyphenation of liquid separation techniques (liquid chromatography, ultra-performance liquid chromatography, SFC) with mass spectrometry (HRMS, IMS, QqQ)
- Principles of separation in liquid phase and their applications for trace analysis in biological matrix
- Metabolomic studies using (U)HPLC/MS
- Analysis of plant material focused on secondary plant materials
- Tandem mass spectrometry, MALDI imaging, ESI/APCI/APPI-MS for characterization of newly synthesized compounds
Publications:
- 27 papers in impacted journals
- 1 chapter in textbook
- 30+ conference and seminar contributions
- 210 citations (without self-citations)
- 9 h-index
10 selected publications:
- Vrba J., Papouskova B., Pyszkova M., Zatloukalova M., Lemr K., Ulrichova J., Vacek J.: Metabolism of palmatine by human hepatocytes and recombinant cytochromes P450. J. Pharm. Biomed. Anal. 102, 193-198 (2015).
- Papouskova B., Fan H., Lemr K., Schug K.A.: Aspects of trapping efficiency and matrix effects in the development of a restricted-access-media-based trap-and-elute liquid chromatography with mass spectrometry method. J. Sep. Sci. 37, 2192-2199 (2014).
- Fan H., Papouskova B., Lemr K., Wigginton J.G., Schug K.A.: Bulk derivatization and direct injection of human cerebrospinal fluid for trace-level quantification of endogenous estrogens using trap-and-elute liquid chromatography with tandem mass spectrometry. J.Sep. Sci. 37, 2010-2017 (2014).
- Vacek J., Papouskova B., Kosina P., Galandakova A ., Ulrichova J.: Mass spectrometric investigation of chelerythrine and dihydrochelerythrine biotransformation patterns in human hepatocytes. J. Chromatogr. B Analyt. Technol. Biomed. Life Sci. 941, 17-24 (2013).
- Vacek J., Papouskova B., Vrba J., Zatloukalova M., Kren V., Ulrichova J.: LC-MS metabolic study on quercetin and taxifolin galloyl esters using human hepatocytes as toxicity and biotransformation in vitro cell model. J. Pharm. Biomed. Anal. 86, 135-142 (2013).
- Vrba, J, Gažák R., Kuzma M., Papoušková B., Vacek J., Weiszenstein M., Křen V., Ulrichová J.:A Novel Semisynthetic Flavonoid 7-O-Galloyltaxifolin Upregulates Heme Oxygenase-1 in RAW264.7 Cells via MAPK/Nrf2 Pathway. J. Med. Chem. 56, 856−866 (2013).
- Papouskova B., Bednar P., Hron K., Stavek, J., Balik, J., Myjavcova, R., Bartak, P., Tomankova, E., Lemr, K.: Advanced liquid chromatography/mass spectrometry profiling of anthocyanins in relation to set of red wine varieties certified in Czech Republic. J. Chromatogr A 1218, 7581-7591 (2011).
- Kosina, P., Vacek, J., Papouskova, B., Stiborova, M., Styskala, J., Cankar, P., Vrublova, E., Vostalova, J., Simanek, V., Ulrichova, J.: Identification of benzo[c]phenanthridine metabolites in human hepatocytes by liquid chromatography with electrospray ion-trap and quadrupole time-of-flight mass spectrometry. J. Chromatogr B 879, 1077-1085 (2011).
- Papoušková B., Bednář P., Fryšová I., Stýskala J., Hlaváč J., Barták P., Ulrichová J., Jirkovský J., Lemr K.: Mass spectrometric study of selected precursors and degradation products of chemical warfare agents. J. Mass Spectrom. 42, 1550–1561 (2007).
- Bednář P., Papoušková B., Műller L., Barták P., Stávek J., Pavloušek P., Lemr K.: Utilization of capillary electrophoresis/mass spectrometry (CE/MSn) for the study of anthocyanin dyes. J. Sep. Sci. 28, 1291-1299 (2005).