Nanotechnology in analytical chemistry
Czech patent no. 307445
The pressure regulation increases pressure in an ion source region. More ions is generated for subsequent measurement and lower limits of quantitation and detection are achieved. The measured signal can be increased by order(s) of magnitude. The proposed design is useful for mass spectrometers or ion mobility spectrometers equipped with atmospheric pressure ion sources.
Study of chromium species release from metal implants in blood and joint effusion: Utilization of HPLC-ICP-MS
Pechancová, R; Pluháček, T; Gallo, J; Milde, D: Study of chromium species release from metal implants in blood and joint effusion: Utilization of HPLC-ICP-MS. Talanta 185 (2018) 370-377. DOI: 10.1016/j.talanta.2018.03.100
The prestigious Hanuš Memorial Medal was awarded to the head of the Department of Analytical Chemistry, prof. RNDr. Karel Lemr, Ph.D, for the results of his scientific work. This recognition of the global contribution to the development of new methods …
A 30-member team of experts in analytical chemistry, history of art and physics will handle the new Arteca project, which aims to develop new methods and techniques vital for research in the sphere of cultural and artistic heritage in the Czech Republic. Link.
Fast and affordable test to detect contamination of drinking water has been developed by chemists from the Department of Analytical Chemistry, Regional Centre of Advanced Technologies and Materials, Palacký University in Olomouc. The tester, a small card, allows determination of chemical as well as microbiological pollution. Its users will be protected from serious health problems caused by contaminated water.
A method of measuring rapid changes of low values of surface conductivity of dielectrics in the environment of electromagnetic interference of mains voltage and a device for performing this method of measuring
On May 24, 2017, The Industrial Property Office of the Czech Republic published in the IPO Bulletin granting of a patent “A method of measuring rapid changes of low values of surface conductivity of dielectrics in the environment of electromagnetic …
Czech Science Foundation project – New Approaches for Monitoring of Transport of Selected Xenobiotics across Biomimetic Membranes
GA ČR (17-05387S) Co-investigator: RNDr. Jana Skopalová, Ph.D. 2017-2019, 110 thousand EUR The project is aimed at development and application of new approaches for monitoring of transport of selected xenobiotics and other biologically important compounds (e.g., drugs, hazardous elements, their …
Czech Science Foundation project – Advanced chemical analysis of residues of organic materials in archaeological context
GAČR 17-17346S Investigator: Assoc. Prof. RNDr. Petr Bednář, Ph.D. 2017- 2019, 4,1 mil. CZK Project is focused on the development of procedures for systematic analysis of organic residues in archaeological findings using top technologies and interpretation of obtained data in …
On 12.7.2017 the R-lab laboratory obtained “A GMP Certificate for A Manufacturer” issued by the State Institute for Drug Control (SÚKL). The laboratory located in the building of the Regional Centre of Advanced Technologies and Materials (RCPTM), has been authorized to perform functions of a control laboratory in the range of chemical/physical quality control tests for human medicines and investigational medicinal products for human use in the field of manufacturing operations and the import of medicinal products.
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Scientific News In Nanotechnology in Analytical Chemistry
Carbon fiber brush electrode as a novel substrate for atmospheric solids analysis probe (ASAP) mass spectrometry: Electrochemical oxidation of brominated phenols >>
Head of the Division:
About the group:
The group focuses on describing and modelling analytical processes during the transition to the nanoscale (the ionization of substances, nanoseparation beds, the influence of nanoparticles on the interaction of radiation and the analyte, electrochemical conversions) and characterizing nanomaterials using the methods of analytical chemistry (e.g. capillary electrophoresis). The group also works on the development of new analytical tools (ion sources, separation systems, sensitive detection systems) and advanced analytical methods (lower detection thresholds, accelerated analyses). Other favoured directions include the development of methods for observing the conversion of toxic and pharmacologically interesting substances, and the description of the interactions of these substances with living organisms. The group is also concerned with basic research on ionization and fragmentation in mass spectrometry, preconcentration, and chromatographic and electrophoretic separation. The knowledge obtained serves as a basis for e.g. analyzing foods or in forensic analysis.
J. Skopalova, P. Bartak, P. Bednar, H. Tomkova, T. Ingr, I. Lorencova, P. Kucerova, R. Papousek, L. Borovcova, K. Lemr: Carbon fiber brush electrode as a novel substrate for atmospheric solids analysis probe (ASAP) mass spectrometry: Electrochemical oxidation of brominated phenols. ANALYTICA CHIMICA ACTA, vol. 999, pp. 60-68, 2018.
V. Pauk, T. Pluhacek, V. Havlicek, K. Lemr: Ultra-high performance supercritical fluid chromatography-mass spectrometry procedure for analysis of monosaccharides from plant gum binders. ANALYTICA CHIMICA ACTA, vol. 989, pp. 112-120, 2017.
V. Melenovsky, J. Petrak, T. Mracek, J. Benes, B.A. Borlaug, H. Nuskova, T. Pluhacek, J. Spatenka, J. Kovalcikova, Z. Drahota, J. Kautzner, J. Pirk, J. Houstek: Myocardial iron content and mitochondrial function in human heart failure: a direct tissue analysis. European Journal of Heart Failure, vol. 19, iss. 4, pp. 522-530, 2017.
T. Mašková, L. Hárendarčíková, J. Petr: Determination of Escherichia coli in urine using a low-cost foil-based microfluidic device. Talanta, vol. 170, pp. 36–40, 2017.
D. Baron, C. Cacho, J. Petr: Electrokinetic preconcentration of magnetite core – carboxylic shell nanoparticles by capillary electrophoresis. Journal of Chromatography A, vol. 1499, pp. 217–221, 2017.
L. Skultety, P. Frycak, Ch. Qiu, J. Smuts, L. Shear-Laude, K. Lemr, J.X. Mao, P. Kroll, K.A. Schug, A. Szewczak, C. Vaught, I. Lurie, V. Havlicek: Resolution of isomeric new designer stimulants using gas chromatography – Vacuum ultraviolet spectroscopy and theoretical Computations. Analytica Chimica Acta, vol. 971, pp. 55-67, 2017.
P. Janoš, J. Henych, J. Pfeifer, N. Zemanová, V. Pilařová, D. Milde, T. Opletal, J. Tolasz, M. Malýd, V. Štengl: Nanocrystalline cerium oxide prepared from a carbonate precursor and its ability to breakdown biologically relevant organophosphates. Environmental Science-Nano, vol. 4, iss. 6, pp. 1283–1293, 2017.
L. Borovcova, M. Hermanova, V. Pauk, M. Šimek, V. Havlíček, K. Lemr: Simple area determination of strongly overlapping ion mobility peaks. Analytica Chimica Acta, vol. 981, pp. 71-79, 2017.
L. Hárendarčíková, D. Baron, A. Šebestová, J. Rozsypal, J. Petr: True lab-in-a-syringe technology for bioassays. TALANTA, vol. 174, pp. 285-288, 2017.
L. Kučera, O. Kurka, P. Barták, P. Bednář: Liquid chromatography/high resolution tandem mass spectrometry – Tool for the study of polyphenol profile changes during micro-scale biogas digestion of grape marcs. CHEMOSPHERE, vol. 166, pp. 463-472, 2017.
D. Riman, K. Spyrou, A.E. Karantzalis, J. Hrbac, M.I. Prodromidis: Glucose sensing on graphite screen-printed electrode modified by sparking of copper nickel alloys. TALANTA, vol. 165, pp. 466-473, 2017.
J. Přichystal, K.A. Schug, K. Lemr, J. Novák, V. Havlíček: Structural Analysis of Natural Products. Anal. Chem., 88 (21), pp 10338–10346, 2016.
M. Švidrnoch, A. Přibylka, V. Bekárek, J. Ševčík, V. Smolka, V. Maier: Enantioseparation of d,l-2-hydroxyglutaric acid by capillaryelectrophoresis with tandem mass spektrometry-Fast and efficienttool for d- and l-2- hydroxyglutaracidurias diagnosis. Journal of Chromatography A, vol. 1467, pp. 383–390, 2016.
M. Jarošová, D. Walaszek, B. Wagner, D. Milde and E. Bulska: Influence of temperature on laser ablation fractionation during ICP-MS analysis for 213 nm and 266 nm laser wavelength micro-sampling. J. Anal. At. Spectrom., vol. 31, pp. 2089–2093, 2016.
P. Kučerová, J. Skopalová*, L. Kučera, J. Táborský, H. Švecová, K. Lemr, P. Cankař, P. Barták: Electrochemical oxidation of 5-hydroxymethyl tolterodine and identification of its oxidation products using liquid chromatography andmass spektrometry. Electrochimica Acta, vol. 215, pp. 617–625, 2016.
J. Znaleziona, D. Drahoňovský, B. Drahoš, J. Ševčík, V. Maier: Novel cationic coating agent for protein separation by capillary electrophoresis. J. Sep. Sci., vol. 39, iss. 12, pp. 2406–2412, 2016.
P. Ginterová, J. Znaleziona*, R. Knob, M. Douša, J. Petr, J. Ševčík: Enantiomeric purity control of R-cinacalcet in pharmaceutical product by capillary electrophoresis. Chemical Papers, vol. 70, iss. 8, pp. 1024–1030, 2016.
B. Papouskova, M. Bernard, J. Ottenschlager, J. Karban, P. Velisek, J. Hrbac, J. Sykora, J. Storch, J. Vacek: A comprehensive LC/MS analysis of novel cyclopentenedione library. Journal of Pharmaceutical and Biomedical Analysis, vol. 128, pp. 342–351, 2016.
O. Kurka, L. Kučera, P. Bednář: Analytical and semipreparative chiral separation of cis-itraconazole on cellulose stationary phases by high-performance liquid chromatography. J. Sep. Sci., vol. 39, iss. 14, pp. 2736–2745, 2016.
P. Fryčák*, L. Hartmanová, I. Lorencová, Karel Lemr: Screening of synthetic phosphodiesterase-5 inhibitors in herbal dietary supplements using transmission-mode desorption electrospray and high-resolution mass spektrometry. J. Mass Spectrom., vol. 51, iss. 5, pp. 358–362, 2016.
J. Znaleziona*, V. Maier: The use of PAMAM dendrimers as a dynamic coating for cyclodextrin mediated enantioseparation of selected basic drugs. Anal. Methods, vol. 8, iss.9, pp. 1968–1972, 2016.
L. Hartmanová, I. Lorencová, M. Volný, P. Fryčák, V. Havlíček, H. Chmelíčková, T. Ingr, K. Lemr: Lateral resolution of desorption nanoelectrospray: a nanospray tip without nebulizing gas as a source of primary charged droplets, Analyst vol. 141, Iss. 7, pp. 2150-2154, 2016.
T. Pluháček, K. Lemr, D. Ghosh, D. Milde, J. Novák, V. Havlíček: Characterization of microbial siderophores by mass spectrometry, MASS SPECTROMETRY REVIEWS vol. 35, Iss. 1, SI, pp. 35-47, 2016.
V. Pauk, V. Žihlová, L. Borovcová, V. Havlíček, K. Schug, K. Lemr: Fast separation of selected cathinones and phenylethylamines by supercritical ﬂuid chromatography, Journal of Chromatography A vol. 1423, pp. 169-176, 2015.
J. Znaleziona, P. Ginterova, J. Petr,P. Ondra, I. Valka, J. Sevcik, J. Chrastina, V. Maier: Determination and identification of synthetic cannabinoids and their metabolites in different matrices by modern analytical techniques, ANALYTICA CHIMICA ACTA vol. 874, pp. 11-25, 2015.
P. Kucerova, J. Skopalova, L. Kucera, J. Hrbac, K. Lemr: Electrochemical oxidation of fesoterodine and identification of its oxidation products using liquid chromatography and mass spektrometry, ELECTROCHIMICA ACTA vol. 159, pp. 131-139, 2015.